Can You Take St. John's Wort and Zinc Together?
No documented interaction was identified between St. John's Wort and zinc in the sources reviewed.
What the interaction means
NCCIH's St. John's Wort page does not mention zinc. Zinc's own NIH fact sheet does not mention St. John's Wort.
No documented interaction was identified in the authoritative sources reviewed. This is not a guarantee that no interaction exists for every dose, formulation, or individual -- it means the sources checked did not document one.
Practical context
Both substances' own current authoritative sources were checked directly, full text, in both directions.
What the sources say
Last reviewed 2026-08-23
Medical information disclaimer: this information is general and educational. It does not diagnose conditions, prescribe treatment, or determine whether a combination is safe for you personally. Follow your prescription label and ask a pharmacist or clinician before starting, stopping, or combining products. Full disclaimer.
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- Zinc and MagnesiumMonitor
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- Zinc and IronMonitor
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- Zinc and CopperMonitor
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- Zinc and Vitamin B12Insufficient evidence
- Zinc and PotassiumInsufficient evidence
- Zinc and MetforminInsufficient evidence
- Zinc and AtorvastatinInsufficient evidence
- Zinc and LevothyroxineInsufficient evidence
- Zinc and LisinoprilInsufficient evidence
- Zinc and SertralineInsufficient evidence
- Zinc and OmeprazoleInsufficient evidence
- Zinc and MelatoninInsufficient evidence
- Zinc and Vitamin DInsufficient evidence
- Zinc and Vitamin KInsufficient evidence
- Zinc and ProbioticsInsufficient evidence
- Zinc and CaffeineInsufficient evidence
- Zinc and CreatineInsufficient evidence
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