Can You Take Copper and St. John's Wort Together?

What the interaction means

The NIH Office of Dietary Supplements' copper fact sheet states plainly: "Copper is not known to interact with any medications." NCCIH's St. John's Wort page does not mention copper.

No documented interaction between Copper and St. John's Wort was identified in the authoritative sources reviewed. This is not a guarantee that no interaction exists for every dose, formulation, or individual -- it means the sources checked did not document one.

Practical context

Copper's own source gives an explicit negative statement, which is why this is rated higher evidence quality.

What the sources say

Related guides

• SSRIs and Supplement Interaction Cautions

Related interactions

• Copper and CiprofloxacinInsufficient evidence
• Copper and ZincMonitor
• Copper and TurmericInsufficient evidence
• Copper and IronInsufficient evidence
• Copper and MagnesiumInsufficient evidence
• Copper and WarfarinInsufficient evidence
• Copper and Vitamin B12Insufficient evidence
• Copper and PotassiumInsufficient evidence
• Copper and CalciumInsufficient evidence
• Copper and AtorvastatinInsufficient evidence
• Copper and SpironolactoneInsufficient evidence
• Copper and Vitamin KInsufficient evidence
• Copper and CoQ10 (Coenzyme Q10)Insufficient evidence
• Copper and MetforminInsufficient evidence
• Copper and LevothyroxineInsufficient evidence
• Copper and LisinoprilInsufficient evidence
• Copper and OmeprazoleInsufficient evidence
• Copper and SertralineInsufficient evidence
• Copper and CreatineInsufficient evidence
• Copper and Vitamin DInsufficient evidence
• Copper and MelatoninInsufficient evidence
• Copper and ProbioticsInsufficient evidence
• Copper and CaffeineInsufficient evidence
• Copper and DoxycyclineInsufficient evidence
• Copper and Folate / Folic AcidInsufficient evidence
• Copper and Omega-3 / Fish OilInsufficient evidence
• Copper and Vitamin EInsufficient evidence
• Copper and AshwagandhaInsufficient evidence
• Copper and LosartanInsufficient evidence
• Copper and AspirinInsufficient evidence
• Copper and AmlodipineInsufficient evidence
• Copper and IbuprofenInsufficient evidence
• Copper and EscitalopramInsufficient evidence
• Copper and Vitamin CInsufficient evidence
• St. John's Wort and CiprofloxacinInsufficient evidence
• St. John's Wort and WarfarinUse caution
• St. John's Wort and SertralineUse caution
• St. John's Wort and Vitamin EInsufficient evidence
• St. John's Wort and Vitamin KInsufficient evidence
• St. John's Wort and PotassiumInsufficient evidence
• St. John's Wort and SpironolactoneInsufficient evidence
• St. John's Wort and OmeprazoleInsufficient evidence
• St. John's Wort and MetforminInsufficient evidence
• St. John's Wort and DoxycyclineInsufficient evidence
• St. John's Wort and CaffeineInsufficient evidence
• St. John's Wort and Vitamin DInsufficient evidence
• St. John's Wort and CreatineInsufficient evidence
• St. John's Wort and Vitamin CInsufficient evidence
• St. John's Wort and CalciumInsufficient evidence
• St. John's Wort and IronInsufficient evidence
• St. John's Wort and MagnesiumInsufficient evidence
• St. John's Wort and Vitamin B12Insufficient evidence
• St. John's Wort and AshwagandhaInsufficient evidence
• St. John's Wort and Omega-3 / Fish OilInsufficient evidence
• St. John's Wort and ZincInsufficient evidence
• St. John's Wort and LisinoprilInsufficient evidence
• St. John's Wort and CoQ10 (Coenzyme Q10)Insufficient evidence
• St. John's Wort and Folate / Folic AcidInsufficient evidence
• St. John's Wort and AtorvastatinMonitor
• St. John's Wort and LosartanInsufficient evidence
• St. John's Wort and MelatoninInsufficient evidence
• St. John's Wort and ProbioticsInsufficient evidence
• St. John's Wort and AspirinInsufficient evidence
• St. John's Wort and AmlodipineInsufficient evidence
• St. John's Wort and LevothyroxineInsufficient evidence
• St. John's Wort and IbuprofenInsufficient evidence
• St. John's Wort and TurmericInsufficient evidence
• St. John's Wort and EscitalopramUse caution