Can You Take Magnesium and Zinc Together?

Very high doses of supplemental zinc can reduce the body's absorption of magnesium.

MonitorEvidence: Moderate

What the interaction means

The NIH Office of Dietary Supplements' magnesium fact sheet states: "Very high doses of zinc supplements can interfere with the body's ability to absorb and regulate magnesium." The zinc fact sheet corroborates this from the other side: "Taking very high doses of supplemental zinc can reduce your body's absorption of magnesium."

Why it may happen

Not further specified by either source beyond the absorption-interference effect described above.

Practical context

Both sources scope this specifically to "very high doses" of supplemental zinc, not typical supplement-label amounts. No specific spacing interval is published in either source, so none is stated here.

What the sources say

Last reviewed 2026-08-22

Medical information disclaimer: this information is general and educational. It does not diagnose conditions, prescribe treatment, or determine whether a combination is safe for you personally. Follow your prescription label and ask a pharmacist or clinician before starting, stopping, or combining products. Full disclaimer.

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