Can I Take These?

Can You Take Magnesium and Sertraline Together?

No documented interaction was identified between magnesium and sertraline in the sources reviewed.

No documented interaction identifiedEvidence: Moderate

See the full Magnesium page and Sertraline page for other reviewed interactions and reference information.

What the interaction means

Sertraline's FDA label mentions magnesium only as 'magnesium stearate,' an inactive tablet ingredient. Magnesium's own established interactions-section record does not name sertraline.

No documented interaction between Magnesium and Sertraline was identified in the authoritative sources reviewed. This is not a guarantee that no interaction exists for every dose, formulation, or individual -- it means the sources checked did not document one.

Practical context

Both substances' current sources were checked; the inactive-ingredient mention was deliberately not treated as a real interaction claim.

What the sources say

Magnesium — Consumer — NIH Office of Dietary SupplementsSertraline Hydrochloride Tablets — FDA Prescribing Information — Via DailyMed, U.S. National Library of Medicine

Last reviewed 2026-08-23

Medical information disclaimer: this information is general and educational. It does not diagnose conditions, prescribe treatment, or determine whether a combination is safe for you personally. Follow your prescription label and ask a pharmacist or clinician before starting, stopping, or combining products. Full disclaimer.

Related guides

Related interactions