Can You Take Creatine and Magnesium Together?
No documented interaction was identified between creatine and magnesium in the sources reviewed.
What the interaction means
NCCIH's bodybuilding-supplements page mentions 'zinc/magnesium aspartate' only inside an unrelated list of other supplement ingredients with no clear evidence of benefit -- not a claim about creatine interacting with magnesium. Magnesium's own established interactions-section record does not name creatine.
No documented interaction was identified in the authoritative sources reviewed. This is not a guarantee that no interaction exists for every dose, formulation, or individual -- it means the sources checked did not document one.
Practical context
Both substances' current sources were checked; the unrelated-ingredient-list mention was deliberately not treated as a real interaction claim.
What the sources say
Last reviewed 2026-08-23
Medical information disclaimer: this information is general and educational. It does not diagnose conditions, prescribe treatment, or determine whether a combination is safe for you personally. Follow your prescription label and ask a pharmacist or clinician before starting, stopping, or combining products. Full disclaimer.
Related interactions
- Creatine and CalciumInsufficient evidence
- Creatine and CiprofloxacinInsufficient evidence
- Creatine and IronInsufficient evidence
- Creatine and SpironolactoneInsufficient evidence
- Creatine and CaffeineInformational
- Creatine and Vitamin KInsufficient evidence
- Creatine and LevothyroxineInsufficient evidence
- Creatine and Vitamin B12Insufficient evidence
- Creatine and CoQ10 (Coenzyme Q10)Insufficient evidence
- Creatine and PotassiumInsufficient evidence
- Creatine and TurmericInsufficient evidence
- Creatine and CopperInsufficient evidence
- Creatine and St. John's WortInsufficient evidence
- Creatine and OmeprazoleInsufficient evidence
- Creatine and ZincInsufficient evidence
- Creatine and LisinoprilInsufficient evidence
- Creatine and DoxycyclineInsufficient evidence
- Creatine and MetforminInsufficient evidence
- Creatine and MelatoninInsufficient evidence
- Creatine and ProbioticsInsufficient evidence
- Creatine and WarfarinInsufficient evidence
- Creatine and SertralineInsufficient evidence
- Creatine and AtorvastatinInsufficient evidence
- Creatine and Vitamin DInsufficient evidence
- Magnesium and CalciumInsufficient evidence
- Magnesium and PotassiumInsufficient evidence
- Magnesium and WarfarinInsufficient evidence
- Magnesium and St. John's WortInsufficient evidence
- Magnesium and ZincMonitor
- Magnesium and CoQ10 (Coenzyme Q10)Insufficient evidence
- Magnesium and ProbioticsInsufficient evidence
- Magnesium and IronInsufficient evidence
- Magnesium and Vitamin B12Insufficient evidence
- Magnesium and MelatoninInsufficient evidence
- Magnesium and CiprofloxacinUse caution
- Magnesium and DoxycyclineUse caution
- Magnesium and OmeprazoleMonitor
- Magnesium and SpironolactoneInsufficient evidence
- Magnesium and CopperInsufficient evidence
- Magnesium and MetforminInsufficient evidence
- Magnesium and Vitamin DInsufficient evidence
- Magnesium and LisinoprilInsufficient evidence
- Magnesium and TurmericInsufficient evidence
- Magnesium and CaffeineInsufficient evidence
- Magnesium and AtorvastatinInsufficient evidence
- Magnesium and Vitamin KInsufficient evidence
- Magnesium and LevothyroxineMonitor
- Magnesium and SertralineInsufficient evidence