Can You Take Creatine and Zinc Together?
No documented interaction was identified between creatine and zinc in the sources reviewed.
See the full Creatine page and Zinc page for other reviewed interactions and reference information.
What the interaction means
NCCIH's bodybuilding-supplements page mentions "zinc/magnesium aspartate" only inside an unrelated list of other supplement ingredients with no clear evidence of benefit -- not a claim about creatine interacting with zinc. Zinc's own NIH fact sheet interactions section (quinolone/tetracycline antibiotics) does not mention creatine.
No documented interaction between Creatine and Zinc was identified in the authoritative sources reviewed. This is not a guarantee that no interaction exists for every dose, formulation, or individual -- it means the sources checked did not document one.
Practical context
Both substances' current sources were checked; the unrelated-ingredient-list mention was deliberately not treated as a real interaction claim.
What the sources say
Last reviewed 2026-08-23
Medical information disclaimer: this information is general and educational. It does not diagnose conditions, prescribe treatment, or determine whether a combination is safe for you personally. Follow your prescription label and ask a pharmacist or clinician before starting, stopping, or combining products. Full disclaimer.
Related guides
Related interactions
- Creatine and CalciumInsufficient evidence
- Creatine and CiprofloxacinInsufficient evidence
- Creatine and IronInsufficient evidence
- Creatine and SpironolactoneInsufficient evidence
- Creatine and MagnesiumInsufficient evidence
- Creatine and CaffeineInformational
- Creatine and Vitamin KInsufficient evidence
- Creatine and LevothyroxineInsufficient evidence
- Creatine and Vitamin B12Insufficient evidence
- Creatine and PotassiumInsufficient evidence
- Creatine and CopperInsufficient evidence
- Creatine and St. John's WortInsufficient evidence
- Creatine and OmeprazoleInsufficient evidence
- Creatine and DoxycyclineInsufficient evidence
- Creatine and MetforminInsufficient evidence
- Creatine and MelatoninInsufficient evidence
- Creatine and SertralineInsufficient evidence
- Creatine and Omega-3 / Fish OilInsufficient evidence
- Creatine and AtorvastatinInsufficient evidence
- Creatine and Vitamin DInsufficient evidence
- Creatine and WarfarinInsufficient evidence
- Creatine and Vitamin EInsufficient evidence
- Creatine and AshwagandhaInsufficient evidence
- Creatine and Folate / Folic AcidInsufficient evidence
- Creatine and LosartanInsufficient evidence
- Creatine and CoQ10 (Coenzyme Q10)Insufficient evidence
- Creatine and AspirinInsufficient evidence
- Creatine and AmlodipineInsufficient evidence
- Creatine and LisinoprilInsufficient evidence
- Creatine and IbuprofenInsufficient evidence
- Creatine and EscitalopramInsufficient evidence
- Creatine and ProbioticsInsufficient evidence
- Creatine and TurmericInsufficient evidence
- Creatine and Vitamin CInsufficient evidence
- Zinc and MagnesiumMonitor
- Zinc and WarfarinInsufficient evidence
- Zinc and IronMonitor
- Zinc and CiprofloxacinUse caution
- Zinc and CopperMonitor
- Zinc and CalciumInsufficient evidence
- Zinc and Vitamin B12Insufficient evidence
- Zinc and PotassiumInsufficient evidence
- Zinc and MetforminInsufficient evidence
- Zinc and AtorvastatinInsufficient evidence
- Zinc and SertralineInsufficient evidence
- Zinc and OmeprazoleInsufficient evidence
- Zinc and MelatoninInsufficient evidence
- Zinc and Vitamin DInsufficient evidence
- Zinc and Vitamin KInsufficient evidence
- Zinc and ProbioticsInsufficient evidence
- Zinc and CaffeineInsufficient evidence
- Zinc and DoxycyclineUse caution
- Zinc and CoQ10 (Coenzyme Q10)Insufficient evidence
- Zinc and TurmericInsufficient evidence
- Zinc and LisinoprilInsufficient evidence
- Zinc and SpironolactoneInsufficient evidence
- Zinc and St. John's WortInsufficient evidence
- Zinc and Omega-3 / Fish OilInsufficient evidence
- Zinc and Folate / Folic AcidInsufficient evidence
- Zinc and AshwagandhaInsufficient evidence
- Zinc and LosartanInsufficient evidence
- Zinc and AspirinInsufficient evidence
- Zinc and LevothyroxineInsufficient evidence
- Zinc and AmlodipineInsufficient evidence
- Zinc and IbuprofenInsufficient evidence
- Zinc and EscitalopramInsufficient evidence
- Zinc and Vitamin CInsufficient evidence
- Zinc and Vitamin EInsufficient evidence