Can I Take These?

Can You Take Metformin and Zinc Together?

No documented interaction was identified between metformin and zinc in the sources reviewed.

No documented interaction identifiedEvidence: Moderate

See the full Metformin page and Zinc page for other reviewed interactions and reference information.

What the interaction means

The NIH Office of Dietary Supplements' zinc fact sheet's interactions section names quinolone and tetracycline antibiotics, penicillamine, and thiazide diuretics -- metformin is not named. Metformin's own FDA label does not mention zinc.

No documented interaction between Metformin and Zinc was identified in the authoritative sources reviewed. This is not a guarantee that no interaction exists for every dose, formulation, or individual -- it means the sources checked did not document one.

Practical context

Both Metformin's and Zinc's own current authoritative sources were checked, in both directions.

What the sources say

Metformin Hydrochloride Tablets, USP — FDA Prescribing Information — Granules Pharmaceuticals Inc. (via DailyMed, U.S. National Library of Medicine)Zinc — Consumer — NIH Office of Dietary Supplements

Last reviewed 2026-08-23

Medical information disclaimer: this information is general and educational. It does not diagnose conditions, prescribe treatment, or determine whether a combination is safe for you personally. Follow your prescription label and ask a pharmacist or clinician before starting, stopping, or combining products. Full disclaimer.

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