Can I Take These?

Can You Take CoQ10 (Coenzyme Q10) and Metformin Together?

No documented interaction was identified between CoQ10 and metformin in the sources reviewed.

No documented interaction identifiedEvidence: Moderate

See the full CoQ10 (Coenzyme Q10) page and Metformin page for other reviewed interactions and reference information.

What the interaction means

NCCIH's CoQ10 page does not mention metformin. Metformin's own FDA label does not mention CoQ10/coenzyme Q10.

No documented interaction between CoQ10 (Coenzyme Q10) and Metformin was identified in the authoritative sources reviewed. This is not a guarantee that no interaction exists for every dose, formulation, or individual -- it means the sources checked did not document one.

Practical context

Both substances' own current authoritative sources were checked directly, in both directions.

What the sources say

Coenzyme Q10 — National Center for Complementary and Integrative Health (NIH)Metformin Hydrochloride Tablets, USP — FDA Prescribing Information — Granules Pharmaceuticals Inc. (via DailyMed, U.S. National Library of Medicine)

Last reviewed 2026-08-23

Medical information disclaimer: this information is general and educational. It does not diagnose conditions, prescribe treatment, or determine whether a combination is safe for you personally. Follow your prescription label and ask a pharmacist or clinician before starting, stopping, or combining products. Full disclaimer.

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