Metformin
A prescription medication used with diet and exercise to improve blood sugar control in type 2 diabetes.
What it is
Metformin hydrochloride tablets are indicated as an adjunct to diet and exercise to improve glycemic control in adults and pediatric patients 10 years of age and older with type 2 diabetes mellitus.
How it is commonly taken
The recommended starting dose is 500 mg orally twice a day or 850 mg once a day, given with meals; the FDA label notes it should be taken with meals to help lessen an upset-stomach side effect.
Known interaction categories
- Monitor
- Insufficient evidence
- Informational
Published interaction pages on this site
Monitor (3)
Informational (1)
Insufficient evidence (31)
- Metformin and AspirinInsufficient evidence
- Metformin and AtorvastatinInsufficient evidence
- Metformin and CaffeineInsufficient evidence
- Metformin and CalciumInsufficient evidence
- Metformin and CiprofloxacinInsufficient evidence
- Metformin and CopperInsufficient evidence
- Metformin and CoQ10 (Coenzyme Q10)Insufficient evidence
- Metformin and CreatineInsufficient evidence
- Metformin and DoxycyclineInsufficient evidence
- Metformin and EscitalopramInsufficient evidence
- Metformin and Folate / Folic AcidInsufficient evidence
- Metformin and IronInsufficient evidence
- Metformin and LevothyroxineInsufficient evidence
- Metformin and LisinoprilInsufficient evidence
- Metformin and LosartanInsufficient evidence
- Metformin and MagnesiumInsufficient evidence
- Metformin and MelatoninInsufficient evidence
- Metformin and Omega-3 / Fish OilInsufficient evidence
- Metformin and OmeprazoleInsufficient evidence
- Metformin and PotassiumInsufficient evidence
- Metformin and ProbioticsInsufficient evidence
- Metformin and SertralineInsufficient evidence
- Metformin and SpironolactoneInsufficient evidence
- Metformin and St. John's WortInsufficient evidence
- Metformin and TurmericInsufficient evidence
- Metformin and Vitamin CInsufficient evidence
- Metformin and Vitamin DInsufficient evidence
- Metformin and Vitamin EInsufficient evidence
- Metformin and Vitamin KInsufficient evidence
- Metformin and WarfarinInsufficient evidence
- Metformin and ZincInsufficient evidence
Sources
Last reviewed 2026-08-22
Medical information disclaimer: this information is general and educational. It does not diagnose conditions, prescribe treatment, or determine whether a combination is safe for you personally. Follow your prescription label and ask a pharmacist or clinician before starting, stopping, or combining products. Full disclaimer.