Can I Take These?

Can You Take Atorvastatin and Metformin Together?

No documented interaction was identified between metformin and atorvastatin in the sources reviewed.

No documented interaction identifiedEvidence: Moderate

See the full Atorvastatin page and Metformin page for other reviewed interactions and reference information.

What the interaction means

Metformin's FDA label names ~19 drugs/classes affecting glycemic control or lactic-acidosis risk (carbonic anhydrase inhibitors, ranolazine, alcohol, diuretics, corticosteroids, and more) -- atorvastatin is not among them. Atorvastatin's own FDA label is mostly CYP3A4-mediated interactions (cyclosporine, gemfibrozil, several CYP3A4 inhibitors, rifampin) -- metformin is not among them either.

No documented interaction between Atorvastatin and Metformin was identified in the authoritative sources reviewed. This is not a guarantee that no interaction exists for every dose, formulation, or individual -- it means the sources checked did not document one.

Practical context

Metformin's and atorvastatin's FDA labels were checked directly, full text, in both directions. Neither drug is metabolized through pathways the other's label names as a concern.

What the sources say

Metformin Hydrochloride Tablets, USP — FDA Prescribing Information — Granules Pharmaceuticals Inc. (via DailyMed, U.S. National Library of Medicine)Atorvastatin Calcium Tablet — FDA Prescribing Information — Zydus Pharmaceuticals USA Inc. (via DailyMed, U.S. National Library of Medicine)

Last reviewed 2026-08-25

Medical information disclaimer: this information is general and educational. It does not diagnose conditions, prescribe treatment, or determine whether a combination is safe for you personally. Follow your prescription label and ask a pharmacist or clinician before starting, stopping, or combining products. Full disclaimer.

Related interactions