Can You Take Atorvastatin and Lisinopril Together?

No documented interaction was identified between lisinopril and atorvastatin in the sources reviewed.

No documented interaction identifiedEvidence: Moderate

See the full Atorvastatin page and Lisinopril page for other reviewed interactions and reference information.

What the interaction means

Lisinopril's FDA label does not mention atorvastatin. Atorvastatin's FDA label's drug-interaction section is mostly CYP3A4-mediated (cyclosporine, gemfibrozil, several CYP3A4 inhibitors, rifampin) -- lisinopril is not among them.

No documented interaction between Atorvastatin and Lisinopril was identified in the authoritative sources reviewed. This is not a guarantee that no interaction exists for every dose, formulation, or individual -- it means the sources checked did not document one.

Practical context

Lisinopril's and atorvastatin's FDA labels were checked directly, full text, in both directions. Lisinopril is not a CYP3A4-mediated concern and is not named.

What the sources say

Last reviewed 2026-08-25

Medical information disclaimer: this information is general and educational. It does not diagnose conditions, prescribe treatment, or determine whether a combination is safe for you personally. Follow your prescription label and ask a pharmacist or clinician before starting, stopping, or combining products. Full disclaimer.

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