Can I Take These?

Can You Take Caffeine and Lisinopril Together?

No documented interaction was identified between caffeine and lisinopril in the sources reviewed.

No documented interaction identifiedEvidence: Moderate

See the full Caffeine page and Lisinopril page for other reviewed interactions and reference information.

What the interaction means

Lisinopril's FDA label names 11 drugs/classes (diuretics, NSAIDs, ARBs, lithium, and others) -- caffeine is not among them. MedlinePlus's caffeine page does not mention lisinopril.

No documented interaction between Caffeine and Lisinopril was identified in the authoritative sources reviewed. This is not a guarantee that no interaction exists for every dose, formulation, or individual -- it means the sources checked did not document one.

Practical context

Lisinopril's FDA label and caffeine's MedlinePlus page were checked directly, full text, in both directions. Caffeine is not among lisinopril's 11 named interaction concerns.

What the sources say

Lisinopril Tablets — FDA Prescribing Information — Prinston Pharmaceutical Inc. (via DailyMed, U.S. National Library of Medicine)Caffeine — MedlinePlus, U.S. National Library of Medicine

Last reviewed 2026-08-25

Medical information disclaimer: this information is general and educational. It does not diagnose conditions, prescribe treatment, or determine whether a combination is safe for you personally. Follow your prescription label and ask a pharmacist or clinician before starting, stopping, or combining products. Full disclaimer.

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