Can You Take Lisinopril and Omeprazole Together?

No documented interaction was identified between lisinopril and omeprazole in the sources reviewed.

No documented interaction identifiedEvidence: Moderate

See the full Lisinopril page and Omeprazole page for other reviewed interactions and reference information.

What the interaction means

Lisinopril's FDA label names 11 drugs/classes (diuretics, NSAIDs, ARBs, lithium, and others) -- omeprazole is not among them. Omeprazole's own FDA label does not mention lisinopril.

No documented interaction between Lisinopril and Omeprazole was identified in the authoritative sources reviewed. This is not a guarantee that no interaction exists for every dose, formulation, or individual -- it means the sources checked did not document one.

Practical context

Lisinopril's and omeprazole's FDA labels were checked directly, full text, in both directions. Neither drug is named in the other's drug-interaction section.

What the sources say

Last reviewed 2026-08-25

Medical information disclaimer: this information is general and educational. It does not diagnose conditions, prescribe treatment, or determine whether a combination is safe for you personally. Follow your prescription label and ask a pharmacist or clinician before starting, stopping, or combining products. Full disclaimer.

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