Can I Take These?

Can You Take Omeprazole and Probiotics Together?

No documented interaction was identified between omeprazole and probiotics in the sources reviewed.

No documented interaction identifiedEvidence: Moderate

What the interaction means

Omeprazole's FDA label does not mention probiotics. NCCIH's probiotics page does not mention omeprazole.

No documented interaction was identified in the authoritative sources reviewed. This is not a guarantee that no interaction exists for every dose, formulation, or individual -- it means the sources checked did not document one.

Practical context

Both substances' own current authoritative sources were checked directly, full text, in both directions.

What the sources say

Omeprazole Delayed-Release Capsules — FDA Prescribing Information — American Health Packaging (via DailyMed, U.S. National Library of Medicine)Probiotics: What You Need To Know — National Center for Complementary and Integrative Health (NIH)

Last reviewed 2026-08-23

Medical information disclaimer: this information is general and educational. It does not diagnose conditions, prescribe treatment, or determine whether a combination is safe for you personally. Follow your prescription label and ask a pharmacist or clinician before starting, stopping, or combining products. Full disclaimer.

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