Can I Take These?

Can You Take Probiotics and Warfarin Together?

No documented interaction was identified between probiotics and warfarin in the sources reviewed.

No documented interaction identifiedEvidence: Moderate

See the full Probiotics page and Warfarin page for other reviewed interactions and reference information.

What the interaction means

Warfarin's FDA label documents its interactions largely through CYP450-enzyme tables (CYP1A2, CYP2C9, CYP3A4 inhibitors/inducers) and specific named drugs -- probiotics are not a CYP-mediated concern and are not named. NCCIH's probiotics page's only medication-related discussion anywhere is research on reducing antibiotic-associated diarrhea, and does not mention warfarin.

No documented interaction between Probiotics and Warfarin was identified in the authoritative sources reviewed. This is not a guarantee that no interaction exists for every dose, formulation, or individual -- it means the sources checked did not document one.

Practical context

Warfarin's FDA label and NCCIH's probiotics page were checked directly, full text, in both directions. Probiotics are not an antibiotic or a CYP-mediated concern, so neither of warfarin's or probiotics' documented interaction patterns apply here.

What the sources say

Warfarin Sodium Tablets — FDA Prescribing Information — Amneal Pharmaceuticals LLC (via DailyMed, U.S. National Library of Medicine)Probiotics: What You Need To Know — National Center for Complementary and Integrative Health (NIH)

Last reviewed 2026-08-25

Medical information disclaimer: this information is general and educational. It does not diagnose conditions, prescribe treatment, or determine whether a combination is safe for you personally. Follow your prescription label and ask a pharmacist or clinician before starting, stopping, or combining products. Full disclaimer.

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