Can I Take These?

Can You Take Losartan and Warfarin Together?

Losartan's FDA label states that clinical studies found no clinically significant drug interaction between losartan and warfarin.

InformationalEvidence: High

See the full Losartan page and Warfarin page for other reviewed interactions and reference information.

What the interaction means

Losartan's FDA prescribing information states in its Clinical Pharmacology section: "No clinically significant drug interactions have been found in studies of losartan potassium with hydrochlorothiazide, digoxin, warfarin, cimetidine and phenobarbital." This is a directly documented, tested finding rather than a source simply being silent on the pair.

Why it may happen

Not applicable -- the label reports that a formal interaction study found no clinically significant effect between the two drugs.

Practical context

This differs from most 'no documented interaction' pairs in this dataset in that it reflects a specific interaction study the label references by name, rather than an absence of any mention. It does not mean no monitoring is ever warranted for a given patient -- only that this specific pairing was formally studied and no clinically significant interaction was found.

What the sources say

Losartan Potassium Tablets — FDA Prescribing Information — Bryant Ranch Prepack (via DailyMed, U.S. National Library of Medicine)

Last reviewed 2026-08-24

Medical information disclaimer: this information is general and educational. It does not diagnose conditions, prescribe treatment, or determine whether a combination is safe for you personally. Follow your prescription label and ask a pharmacist or clinician before starting, stopping, or combining products. Full disclaimer.

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