Losartan
A prescription angiotensin II receptor blocker (ARB) used to treat high blood pressure and, in some patients, to reduce stroke risk or slow diabetic kidney disease.
What it is
Losartan is an angiotensin II receptor blocker (ARB). The FDA label states it is indicated for: "Treatment of hypertension, to lower blood pressure in adults and children greater than 6 years old"; "Reduction of the risk of stroke in patients with hypertension and left ventricular hypertrophy"; and "Treatment of diabetic nephropathy with an elevated serum creatinine and proteinuria in patients with type 2 diabetes and a history of hypertension." Like other drugs acting on the renin-angiotensin system, it reduces aldosterone, which can raise blood potassium levels.
How it is commonly taken
The usual starting dose for hypertension is 50 mg once daily, which can be increased to a maximum of 100 mg once daily as needed to control blood pressure, per the FDA label.
Known interaction categories
- Insufficient evidence
- Avoid combining
- Monitor
- Informational
- Use caution
Published interaction pages on this site
Avoid combining (1)
Use caution (1)
Monitor (4)
Informational (1)
Insufficient evidence (28)
- Losartan and AmlodipineInsufficient evidence
- Losartan and AtorvastatinInsufficient evidence
- Losartan and CaffeineInsufficient evidence
- Losartan and CalciumInsufficient evidence
- Losartan and CiprofloxacinInsufficient evidence
- Losartan and CopperInsufficient evidence
- Losartan and CoQ10 (Coenzyme Q10)Insufficient evidence
- Losartan and CreatineInsufficient evidence
- Losartan and DoxycyclineInsufficient evidence
- Losartan and EscitalopramInsufficient evidence
- Losartan and Folate / Folic AcidInsufficient evidence
- Losartan and IronInsufficient evidence
- Losartan and LevothyroxineInsufficient evidence
- Losartan and MagnesiumInsufficient evidence
- Losartan and MelatoninInsufficient evidence
- Losartan and MetforminInsufficient evidence
- Losartan and Omega-3 / Fish OilInsufficient evidence
- Losartan and OmeprazoleInsufficient evidence
- Losartan and ProbioticsInsufficient evidence
- Losartan and SertralineInsufficient evidence
- Losartan and St. John's WortInsufficient evidence
- Losartan and TurmericInsufficient evidence
- Losartan and Vitamin B12Insufficient evidence
- Losartan and Vitamin CInsufficient evidence
- Losartan and Vitamin DInsufficient evidence
- Losartan and Vitamin EInsufficient evidence
- Losartan and Vitamin KInsufficient evidence
- Losartan and ZincInsufficient evidence
Related guides
Sources
Last reviewed 2026-08-24
Medical information disclaimer: this information is general and educational. It does not diagnose conditions, prescribe treatment, or determine whether a combination is safe for you personally. Follow your prescription label and ask a pharmacist or clinician before starting, stopping, or combining products. Full disclaimer.