Can I Take These?

Can You Take Amlodipine and Losartan Together?

No documented interaction was identified between losartan and amlodipine in the sources reviewed.

No documented interaction identifiedEvidence: Moderate

See the full Amlodipine page and Losartan page for other reviewed interactions and reference information.

What the interaction means

Losartan's FDA prescribing information does not mention amlodipine or calcium channel blockers anywhere; its named interacting classes are agents that raise serum potassium, lithium, NSAIDs/COX-2 inhibitors, and dual RAS blockade with ACE inhibitors/aliskiren. Losartan's MedlinePlus page also does not mention amlodipine. Amlodipine's own FDA prescribing information (Norvasc) does not mention losartan, ARBs, or angiotensin receptor blockers anywhere, and its MedlinePlus page gives only general medication-disclosure guidance without naming losartan.

No documented interaction was identified in the authoritative sources reviewed. This is not a guarantee that no interaction exists for every dose, formulation, or individual -- it means the sources checked did not document one.

Practical context

Both substances' own current authoritative sources were checked directly, full text, in both directions. Losartan and amlodipine are commonly co-prescribed together for blood pressure control, but no direct pharmacological interaction between them is documented in the sources reviewed.

What the sources say

Amlodipine — MedlinePlus, U.S. National Library of MedicineLosartan Potassium Tablets — FDA Prescribing Information — Granules Pharmaceuticals, Inc. (via DailyMed, U.S. National Library of Medicine)Norvasc (Amlodipine Besylate) Tablets — FDA Prescribing Information — Pfizer Laboratories Division, Pfizer Inc. (via DailyMed, U.S. National Library of Medicine)Losartan — MedlinePlus, U.S. National Library of Medicine

Last reviewed 2026-08-24

Medical information disclaimer: this information is general and educational. It does not diagnose conditions, prescribe treatment, or determine whether a combination is safe for you personally. Follow your prescription label and ask a pharmacist or clinician before starting, stopping, or combining products. Full disclaimer.

Related interactions