Can I Take These?

Can You Take Levothyroxine and Losartan Together?

No documented interaction was identified between losartan and levothyroxine in the sources reviewed.

No documented interaction identifiedEvidence: Moderate

See the full Levothyroxine page and Losartan page for other reviewed interactions and reference information.

What the interaction means

Losartan's FDA label documents four drug-interaction categories -- potassium-raising drugs, lithium, NSAIDs, and dual RAS blockade with other ARBs/ACE inhibitors -- and levothyroxine or thyroid hormone is not among them. Levothyroxine's own FDA label does not mention losartan, ARBs, or angiotensin.

No documented interaction between Levothyroxine and Losartan was identified in the authoritative sources reviewed. This is not a guarantee that no interaction exists for every dose, formulation, or individual -- it means the sources checked did not document one.

Practical context

Losartan's FDA label and levothyroxine's FDA label were checked directly, full text, in both directions. Losartan's own named interaction categories do not include thyroid hormone medications.

What the sources say

Losartan Potassium Tablets — FDA Prescribing Information — Bryant Ranch Prepack (via DailyMed, U.S. National Library of Medicine)Levothyroxine Sodium Tablets — FDA Prescribing Information — via DailyMed, U.S. National Library of Medicine

Last reviewed 2026-08-25

Medical information disclaimer: this information is general and educational. It does not diagnose conditions, prescribe treatment, or determine whether a combination is safe for you personally. Follow your prescription label and ask a pharmacist or clinician before starting, stopping, or combining products. Full disclaimer.

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