Can I Take These?

Can You Take Atorvastatin and Levothyroxine Together?

No documented interaction was identified between atorvastatin and levothyroxine in the sources reviewed.

No documented interaction identifiedEvidence: Moderate

See the full Atorvastatin page and Levothyroxine page for other reviewed interactions and reference information.

What the interaction means

Atorvastatin's FDA label's drug-interaction section is mostly CYP3A4-mediated (cyclosporine, gemfibrozil, several CYP3A4 inhibitors, rifampin) -- levothyroxine is not among them. Levothyroxine's own extensive drug-interaction section (absorption, protein-transport, and metabolism effects) does not name atorvastatin or statins either.

No documented interaction between Atorvastatin and Levothyroxine was identified in the authoritative sources reviewed. This is not a guarantee that no interaction exists for every dose, formulation, or individual -- it means the sources checked did not document one.

Practical context

Atorvastatin's and levothyroxine's FDA labels were checked directly, full text, in both directions. Neither drug is named in the other's drug-interaction section.

What the sources say

Levothyroxine Sodium Capsules — FDA Prescribing Information — YARAL Pharma, Inc. (via DailyMed, U.S. National Library of Medicine)Atorvastatin Calcium Tablet — FDA Prescribing Information — Zydus Pharmaceuticals USA Inc. (via DailyMed, U.S. National Library of Medicine)

Last reviewed 2026-08-25

Medical information disclaimer: this information is general and educational. It does not diagnose conditions, prescribe treatment, or determine whether a combination is safe for you personally. Follow your prescription label and ask a pharmacist or clinician before starting, stopping, or combining products. Full disclaimer.

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