Can I Take These?

Can You Take Atorvastatin and Spironolactone Together?

No documented interaction was identified between atorvastatin and spironolactone in the sources reviewed.

No documented interaction identifiedEvidence: Moderate

See the full Atorvastatin page and Spironolactone page for other reviewed interactions and reference information.

What the interaction means

Neither atorvastatin's nor spironolactone's FDA label mentions the other substance anywhere.

No documented interaction between Atorvastatin and Spironolactone was identified in the authoritative sources reviewed. This is not a guarantee that no interaction exists for every dose, formulation, or individual -- it means the sources checked did not document one.

Practical context

Both Atorvastatin's and Spironolactone's own current FDA labels were checked directly, full text, in both directions.

What the sources say

Spironolactone Tablets — FDA Prescribing Information — Sun Pharmaceutical Industries, Inc. (via DailyMed, U.S. National Library of Medicine)Atorvastatin Calcium Tablet — FDA Prescribing Information — Zydus Pharmaceuticals USA Inc. (via DailyMed, U.S. National Library of Medicine)

Last reviewed 2026-08-23

Medical information disclaimer: this information is general and educational. It does not diagnose conditions, prescribe treatment, or determine whether a combination is safe for you personally. Follow your prescription label and ask a pharmacist or clinician before starting, stopping, or combining products. Full disclaimer.

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