Can I Take These?

Can You Take Atorvastatin and Spironolactone Together?

No documented interaction was identified between atorvastatin and spironolactone in the sources reviewed.

No documented interaction identifiedEvidence: Moderate

What the interaction means

Neither atorvastatin's nor spironolactone's FDA label mentions the other substance anywhere.

No documented interaction was identified in the authoritative sources reviewed. This is not a guarantee that no interaction exists for every dose, formulation, or individual -- it means the sources checked did not document one.

Practical context

Both substances' own current FDA labels were checked directly, full text, in both directions.

What the sources say

Spironolactone Tablets — FDA Prescribing Information — Sun Pharmaceutical Industries, Inc. (via DailyMed, U.S. National Library of Medicine)Atorvastatin Calcium Tablet — FDA Prescribing Information — Zydus Pharmaceuticals USA Inc. (via DailyMed, U.S. National Library of Medicine)

Last reviewed 2026-08-23

Medical information disclaimer: this information is general and educational. It does not diagnose conditions, prescribe treatment, or determine whether a combination is safe for you personally. Follow your prescription label and ask a pharmacist or clinician before starting, stopping, or combining products. Full disclaimer.

Related interactions