Spironolactone

What it is

Spironolactone is a potassium-sparing diuretic (water pill) prescribed for conditions such as edema, hypertension, and heart failure. Unlike some other diuretics, it works in a way that causes the body to retain potassium rather than lose it, which is the basis for its interaction with potassium supplements.

Known interaction categories

• Insufficient evidence
• Avoid combining
• Use caution

Published interaction pages on this site

• Spironolactone and IronInsufficient evidence
• Spironolactone and PotassiumAvoid combining
• Spironolactone and CalciumInsufficient evidence
• Spironolactone and CoQ10 (Coenzyme Q10)Insufficient evidence
• Spironolactone and CiprofloxacinInsufficient evidence
• Spironolactone and MagnesiumInsufficient evidence
• Spironolactone and CreatineInsufficient evidence
• Spironolactone and CaffeineInsufficient evidence
• Spironolactone and Vitamin KInsufficient evidence
• Spironolactone and LevothyroxineInsufficient evidence
• Spironolactone and TurmericInsufficient evidence
• Spironolactone and WarfarinInsufficient evidence
• Spironolactone and St. John's WortInsufficient evidence
• Spironolactone and CopperInsufficient evidence
• Spironolactone and SertralineInsufficient evidence
• Spironolactone and MelatoninInsufficient evidence
• Spironolactone and MetforminInsufficient evidence
• Spironolactone and ProbioticsInsufficient evidence
• Spironolactone and Vitamin DInsufficient evidence
• Spironolactone and ZincInsufficient evidence
• Spironolactone and DoxycyclineInsufficient evidence
• Spironolactone and OmeprazoleInsufficient evidence
• Spironolactone and Vitamin B12Insufficient evidence
• Spironolactone and AtorvastatinInsufficient evidence
• Spironolactone and LisinoprilUse caution

Sources