Can You Take Iron and Spironolactone Together?
No documented interaction was identified between iron and spironolactone in the sources reviewed.
What the interaction means
Spironolactone's FDA label does not mention iron. Iron's own NIH fact sheet does not mention spironolactone.
No documented interaction was identified in the authoritative sources reviewed. This is not a guarantee that no interaction exists for every dose, formulation, or individual -- it means the sources checked did not document one.
Practical context
Both substances' own current authoritative sources were checked directly, full text, in both directions.
What the sources say
Last reviewed 2026-08-23
Medical information disclaimer: this information is general and educational. It does not diagnose conditions, prescribe treatment, or determine whether a combination is safe for you personally. Follow your prescription label and ask a pharmacist or clinician before starting, stopping, or combining products. Full disclaimer.
Related interactions
- Iron and WarfarinInsufficient evidence
- Iron and OmeprazoleMonitor
- Iron and CalciumMonitor
- Iron and PotassiumInsufficient evidence
- Iron and CaffeineInsufficient evidence
- Iron and ZincMonitor
- Iron and LevothyroxineUse caution
- Iron and MagnesiumInsufficient evidence
- Iron and DoxycyclineUse caution
- Iron and CiprofloxacinUse caution
- Iron and Vitamin B12Insufficient evidence
- Iron and Vitamin DInsufficient evidence
- Iron and St. John's WortInsufficient evidence
- Iron and ProbioticsInsufficient evidence
- Iron and CopperInsufficient evidence
- Iron and TurmericInsufficient evidence
- Iron and MetforminInsufficient evidence
- Iron and CoQ10 (Coenzyme Q10)Insufficient evidence
- Iron and Vitamin KInsufficient evidence
- Iron and CreatineInsufficient evidence
- Iron and AtorvastatinInsufficient evidence
- Iron and MelatoninInsufficient evidence
- Iron and LisinoprilInsufficient evidence
- Iron and SertralineInsufficient evidence
- Spironolactone and PotassiumAvoid combining
- Spironolactone and CalciumInsufficient evidence
- Spironolactone and CoQ10 (Coenzyme Q10)Insufficient evidence
- Spironolactone and CiprofloxacinInsufficient evidence
- Spironolactone and MagnesiumInsufficient evidence
- Spironolactone and CreatineInsufficient evidence
- Spironolactone and CaffeineInsufficient evidence
- Spironolactone and Vitamin KInsufficient evidence
- Spironolactone and LevothyroxineInsufficient evidence
- Spironolactone and TurmericInsufficient evidence
- Spironolactone and WarfarinInsufficient evidence
- Spironolactone and St. John's WortInsufficient evidence
- Spironolactone and CopperInsufficient evidence
- Spironolactone and SertralineInsufficient evidence
- Spironolactone and MelatoninInsufficient evidence
- Spironolactone and MetforminInsufficient evidence
- Spironolactone and ProbioticsInsufficient evidence
- Spironolactone and Vitamin DInsufficient evidence
- Spironolactone and ZincInsufficient evidence
- Spironolactone and DoxycyclineInsufficient evidence
- Spironolactone and OmeprazoleInsufficient evidence
- Spironolactone and Vitamin B12Insufficient evidence
- Spironolactone and AtorvastatinInsufficient evidence
- Spironolactone and LisinoprilUse caution