Can You Take Spironolactone and Vitamin D Together?

What the interaction means

Spironolactone's FDA label's only 'vitamin D' hit is 'PROVITAMIN D2 COMPOUND' inside its generic pharmacologic-class taxonomy dropdown, not a prose interaction statement. Vitamin D's own MedlinePlus page does not mention spironolactone.

No documented interaction between Spironolactone and Vitamin D was identified in the authoritative sources reviewed. This is not a guarantee that no interaction exists for every dose, formulation, or individual -- it means the sources checked did not document one.

Practical context

Both substances' own current authoritative sources were checked, in both directions; the taxonomy-list mention was deliberately not treated as a real interaction claim.

What the sources say

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Related interactions

• Spironolactone and PotassiumAvoid combining
• Spironolactone and CalciumInsufficient evidence
• Spironolactone and CoQ10 (Coenzyme Q10)Insufficient evidence
• Spironolactone and CiprofloxacinInsufficient evidence
• Spironolactone and MagnesiumInsufficient evidence
• Spironolactone and Vitamin EInsufficient evidence
• Spironolactone and CreatineInsufficient evidence
• Spironolactone and CaffeineInsufficient evidence
• Spironolactone and Vitamin KInsufficient evidence
• Spironolactone and TurmericInsufficient evidence
• Spironolactone and WarfarinInsufficient evidence
• Spironolactone and St. John's WortInsufficient evidence
• Spironolactone and CopperInsufficient evidence
• Spironolactone and SertralineInsufficient evidence
• Spironolactone and MelatoninInsufficient evidence
• Spironolactone and MetforminInsufficient evidence
• Spironolactone and DoxycyclineInsufficient evidence
• Spironolactone and OmeprazoleInsufficient evidence
• Spironolactone and Vitamin B12Insufficient evidence
• Spironolactone and IronInsufficient evidence
• Spironolactone and AtorvastatinInsufficient evidence
• Spironolactone and LisinoprilUse caution
• Spironolactone and ZincInsufficient evidence
• Spironolactone and Omega-3 / Fish OilInsufficient evidence
• Spironolactone and AshwagandhaMonitor
• Spironolactone and ProbioticsInsufficient evidence
• Spironolactone and AspirinMonitor
• Spironolactone and Vitamin CInsufficient evidence
• Spironolactone and LevothyroxineInsufficient evidence
• Spironolactone and AmlodipineInsufficient evidence
• Spironolactone and EscitalopramInsufficient evidence
• Spironolactone and Folate / Folic AcidInsufficient evidence
• Spironolactone and IbuprofenUse caution
• Spironolactone and LosartanUse caution
• Vitamin D and CalciumInformational
• Vitamin D and IronInsufficient evidence
• Vitamin D and CiprofloxacinInsufficient evidence
• Vitamin D and LevothyroxineInsufficient evidence
• Vitamin D and MagnesiumInsufficient evidence
• Vitamin D and WarfarinInsufficient evidence
• Vitamin D and Vitamin B12Insufficient evidence
• Vitamin D and PotassiumInsufficient evidence
• Vitamin D and St. John's WortInsufficient evidence
• Vitamin D and DoxycyclineInsufficient evidence
• Vitamin D and CopperInsufficient evidence
• Vitamin D and TurmericInsufficient evidence
• Vitamin D and LisinoprilInsufficient evidence
• Vitamin D and ZincInsufficient evidence
• Vitamin D and ProbioticsInsufficient evidence
• Vitamin D and MelatoninInsufficient evidence
• Vitamin D and OmeprazoleInsufficient evidence
• Vitamin D and SertralineInsufficient evidence
• Vitamin D and AtorvastatinInsufficient evidence
• Vitamin D and CaffeineInsufficient evidence
• Vitamin D and CreatineInsufficient evidence
• Vitamin D and AshwagandhaInsufficient evidence
• Vitamin D and Omega-3 / Fish OilInsufficient evidence
• Vitamin D and Folate / Folic AcidInsufficient evidence
• Vitamin D and LosartanInsufficient evidence
• Vitamin D and AspirinInsufficient evidence
• Vitamin D and Vitamin CInsufficient evidence
• Vitamin D and CoQ10 (Coenzyme Q10)Insufficient evidence
• Vitamin D and AmlodipineInsufficient evidence
• Vitamin D and IbuprofenInsufficient evidence
• Vitamin D and MetforminInsufficient evidence
• Vitamin D and EscitalopramInsufficient evidence
• Vitamin D and Vitamin KInsufficient evidence
• Vitamin D and Vitamin EInsufficient evidence