Can You Take Caffeine and Vitamin D Together?
No documented interaction was identified between vitamin D and caffeine in the sources reviewed.
See the full Caffeine page and Vitamin D page for other reviewed interactions and reference information.
What the interaction means
MedlinePlus's vitamin D page does not mention caffeine. MedlinePlus's caffeine page does not mention vitamin D or fat-soluble vitamins.
No documented interaction between Caffeine and Vitamin D was identified in the authoritative sources reviewed. This is not a guarantee that no interaction exists for every dose, formulation, or individual -- it means the sources checked did not document one.
Practical context
Vitamin D's and caffeine's MedlinePlus pages were checked directly, full text, in both directions. Neither page raises a caution about combining them.
What the sources say
Last reviewed 2026-08-25
Medical information disclaimer: this information is general and educational. It does not diagnose conditions, prescribe treatment, or determine whether a combination is safe for you personally. Follow your prescription label and ask a pharmacist or clinician before starting, stopping, or combining products. Full disclaimer.
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- Vitamin D and Omega-3 / Fish OilInsufficient evidence
- Vitamin D and Folate / Folic AcidInsufficient evidence
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- Vitamin D and AspirinInsufficient evidence
- Vitamin D and Vitamin CInsufficient evidence
- Vitamin D and CoQ10 (Coenzyme Q10)Insufficient evidence
- Vitamin D and AmlodipineInsufficient evidence
- Vitamin D and IbuprofenInsufficient evidence
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