Can I Take These?

Can You Take Caffeine and Escitalopram Together?

No documented interaction was identified between escitalopram and caffeine in the sources reviewed.

No documented interaction identifiedEvidence: Moderate

See the full Caffeine page and Escitalopram page for other reviewed interactions and reference information.

What the interaction means

Escitalopram's own FDA label does not name caffeine anywhere in its Drug Interactions section. MedlinePlus's caffeine page does not mention escitalopram, citalopram, SSRI, serotonin, or antidepressant.

No documented interaction was identified in the authoritative sources reviewed. This is not a guarantee that no interaction exists for every dose, formulation, or individual -- it means the sources checked did not document one.

Practical context

Both substances' own current authoritative sources were checked directly, full text, in both directions.

What the sources say

Caffeine — MedlinePlus, U.S. National Library of MedicineLEXAPRO (escitalopram) Tablets and Oral Solution — FDA Prescribing Information — Allergan, Inc. (via DailyMed, U.S. National Library of Medicine)

Last reviewed 2026-08-24

Medical information disclaimer: this information is general and educational. It does not diagnose conditions, prescribe treatment, or determine whether a combination is safe for you personally. Follow your prescription label and ask a pharmacist or clinician before starting, stopping, or combining products. Full disclaimer.

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