Can I Take These?

Can You Take Escitalopram and Lisinopril Together?

No documented interaction was identified between escitalopram and lisinopril in the sources reviewed.

No documented interaction identifiedEvidence: Moderate

See the full Escitalopram page and Lisinopril page for other reviewed interactions and reference information.

What the interaction means

Escitalopram's own FDA label does not name lisinopril anywhere in its Drug Interactions section. Lisinopril's own FDA label does not mention escitalopram, citalopram, SSRI, serotonin, or antidepressant; hyponatremia appears only as lisinopril's own post-marketing adverse reaction, not tied to any antidepressant interaction.

No documented interaction was identified in the authoritative sources reviewed. This is not a guarantee that no interaction exists for every dose, formulation, or individual -- it means the sources checked did not document one.

Practical context

Both substances' own current authoritative sources were checked directly, full text, in both directions.

What the sources say

Lisinopril Tablets — FDA Prescribing Information — Prinston Pharmaceutical Inc. (via DailyMed, U.S. National Library of Medicine)LEXAPRO (escitalopram) Tablets and Oral Solution — FDA Prescribing Information — Allergan, Inc. (via DailyMed, U.S. National Library of Medicine)

Last reviewed 2026-08-24

Medical information disclaimer: this information is general and educational. It does not diagnose conditions, prescribe treatment, or determine whether a combination is safe for you personally. Follow your prescription label and ask a pharmacist or clinician before starting, stopping, or combining products. Full disclaimer.

Related interactions