Can I Take These?

Can You Take Lisinopril and Probiotics Together?

No documented interaction was identified between lisinopril and probiotics in the sources reviewed.

No documented interaction identifiedEvidence: Moderate

See the full Lisinopril page and Probiotics page for other reviewed interactions and reference information.

What the interaction means

Lisinopril's FDA label names 11 drugs/classes (diuretics, NSAIDs, ARBs, lithium, and others) -- probiotics are not among them. NCCIH's probiotics page's only medication-related discussion anywhere is research on reducing antibiotic-associated diarrhea, and does not mention lisinopril.

No documented interaction between Lisinopril and Probiotics was identified in the authoritative sources reviewed. This is not a guarantee that no interaction exists for every dose, formulation, or individual -- it means the sources checked did not document one.

Practical context

Lisinopril's FDA label and NCCIH's probiotics page were checked directly, full text, in both directions. Lisinopril is not an antibiotic, so probiotics' one documented medication-related finding does not apply here.

What the sources say

Lisinopril Tablets — FDA Prescribing Information — Prinston Pharmaceutical Inc. (via DailyMed, U.S. National Library of Medicine)Probiotics: What You Need To Know — National Center for Complementary and Integrative Health (NIH)

Last reviewed 2026-08-25

Medical information disclaimer: this information is general and educational. It does not diagnose conditions, prescribe treatment, or determine whether a combination is safe for you personally. Follow your prescription label and ask a pharmacist or clinician before starting, stopping, or combining products. Full disclaimer.

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