Can I Take These?

Can You Take Calcium and Probiotics Together?

No documented interaction was identified between calcium and probiotics in the sources reviewed.

No documented interaction identifiedEvidence: Moderate

See the full Calcium page and Probiotics page for other reviewed interactions and reference information.

What the interaction means

NCCIH's probiotics page's only medication-related discussion anywhere is research on reducing antibiotic-associated diarrhea, and does not mention calcium. Calcium's own NIH ODS fact sheet names dolutegravir, levothyroxine, lithium, and quinolone antibiotics as its documented drug interactions -- probiotics are not among them.

No documented interaction between Calcium and Probiotics was identified in the authoritative sources reviewed. This is not a guarantee that no interaction exists for every dose, formulation, or individual -- it means the sources checked did not document one.

Practical context

NCCIH's probiotics page and calcium's NIH ODS fact sheet were checked directly, full text, in both directions. Neither source names the other.

What the sources say

Calcium — Consumer — NIH Office of Dietary SupplementsProbiotics: What You Need To Know — National Center for Complementary and Integrative Health (NIH)

Last reviewed 2026-08-25

Medical information disclaimer: this information is general and educational. It does not diagnose conditions, prescribe treatment, or determine whether a combination is safe for you personally. Follow your prescription label and ask a pharmacist or clinician before starting, stopping, or combining products. Full disclaimer.

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