Can I Take These?

Can You Take Calcium and Sertraline Together?

No documented interaction was identified between calcium and sertraline in the sources reviewed.

No documented interaction identifiedEvidence: Moderate

See the full Calcium page and Sertraline page for other reviewed interactions and reference information.

What the interaction means

Sertraline's FDA label's Drug Interactions section covers protein-bound drugs (e.g. warfarin) and CYP2D6 substrates -- calcium is not among them (its only "calcium" appearances are an inactive-ingredient listing and the label's generic pharmacologic-class taxonomy list). Calcium's own NIH fact sheet does not mention sertraline.

No documented interaction between Calcium and Sertraline was identified in the authoritative sources reviewed. This is not a guarantee that no interaction exists for every dose, formulation, or individual -- it means the sources checked did not document one.

Practical context

Both substances' own current authoritative sources were checked directly, full text, in both directions; taxonomy-list and inactive-ingredient mentions were deliberately not treated as interaction claims.

What the sources say

Sertraline Hydrochloride Tablets — FDA Prescribing Information — Via DailyMed, U.S. National Library of MedicineCalcium — Consumer — NIH Office of Dietary Supplements

Last reviewed 2026-08-23

Medical information disclaimer: this information is general and educational. It does not diagnose conditions, prescribe treatment, or determine whether a combination is safe for you personally. Follow your prescription label and ask a pharmacist or clinician before starting, stopping, or combining products. Full disclaimer.

Related guides

Related interactions