Can I Take These?

Can You Take Sertraline and Zinc Together?

No documented interaction was identified between zinc and sertraline in the sources reviewed.

No documented interaction identifiedEvidence: Moderate

See the full Sertraline page and Zinc page for other reviewed interactions and reference information.

What the interaction means

The NIH ODS zinc fact sheet's interactions section names quinolone/tetracycline antibiotics, penicillamine, and thiazide diuretics specifically, not sertraline. Sertraline's FDA label does not mention zinc.

No documented interaction between Sertraline and Zinc was identified in the authoritative sources reviewed. This is not a guarantee that no interaction exists for every dose, formulation, or individual -- it means the sources checked did not document one.

Practical context

Both Sertraline's and Zinc's own current authoritative sources were checked, in both directions.

What the sources say

Sertraline Hydrochloride Tablets — FDA Prescribing Information — Via DailyMed, U.S. National Library of MedicineZinc — Consumer — NIH Office of Dietary Supplements

Last reviewed 2026-08-23

Medical information disclaimer: this information is general and educational. It does not diagnose conditions, prescribe treatment, or determine whether a combination is safe for you personally. Follow your prescription label and ask a pharmacist or clinician before starting, stopping, or combining products. Full disclaimer.

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