Can I Take These?

Can You Take Sertraline and Zinc Together?

No documented interaction was identified between zinc and sertraline in the sources reviewed.

No documented interaction identifiedEvidence: Moderate

What the interaction means

The NIH ODS zinc fact sheet's interactions section names quinolone/tetracycline antibiotics, penicillamine, and thiazide diuretics specifically, not sertraline. Sertraline's FDA label does not mention zinc.

No documented interaction was identified in the authoritative sources reviewed. This is not a guarantee that no interaction exists for every dose, formulation, or individual -- it means the sources checked did not document one.

Practical context

Both substances' own current authoritative sources were checked, in both directions.

What the sources say

Sertraline Hydrochloride Tablets — FDA Prescribing Information — Via DailyMed, U.S. National Library of MedicineZinc — Consumer — NIH Office of Dietary Supplements

Last reviewed 2026-08-23

Medical information disclaimer: this information is general and educational. It does not diagnose conditions, prescribe treatment, or determine whether a combination is safe for you personally. Follow your prescription label and ask a pharmacist or clinician before starting, stopping, or combining products. Full disclaimer.

Related interactions