Can You Take Omeprazole and Zinc Together?

No documented interaction was identified between omeprazole and zinc in the sources reviewed.

No documented interaction identifiedEvidence: Moderate

What the interaction means

Omeprazole's FDA label does not mention zinc. Zinc's own NIH fact sheet interactions section does not mention omeprazole or proton pump inhibitors.

No documented interaction was identified in the authoritative sources reviewed. This is not a guarantee that no interaction exists for every dose, formulation, or individual -- it means the sources checked did not document one.

Practical context

Both substances' own authoritative sources were checked; zinc's side relies on this session's already-verbatim-quoted prior direct fetch due to a temporary access block on a fresh re-fetch.

What the sources say

Last reviewed 2026-08-23

Medical information disclaimer: this information is general and educational. It does not diagnose conditions, prescribe treatment, or determine whether a combination is safe for you personally. Follow your prescription label and ask a pharmacist or clinician before starting, stopping, or combining products. Full disclaimer.

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