Omeprazole
A prescription and over-the-counter proton pump inhibitor (PPI) used to reduce stomach acid.
What it is
Omeprazole is a proton pump inhibitor (PPI) that reduces stomach acid production, used to treat conditions such as gastroesophageal reflux disease (GERD), ulcers, and related acid-related conditions. Long-term acid suppression from PPIs is documented to affect absorption of certain nutrients, discussed on the interaction pages linked below.
Known interaction categories
- Monitor
- Insufficient evidence
- Use caution
Published interaction pages on this site
- Omeprazole and IronMonitor
- Omeprazole and MelatoninInsufficient evidence
- Omeprazole and CaffeineInsufficient evidence
- Omeprazole and CiprofloxacinInsufficient evidence
- Omeprazole and Vitamin B12Monitor
- Omeprazole and CalciumMonitor
- Omeprazole and MagnesiumMonitor
- Omeprazole and WarfarinUse caution
- Omeprazole and St. John's WortInsufficient evidence
- Omeprazole and AtorvastatinInsufficient evidence
- Omeprazole and SertralineInsufficient evidence
- Omeprazole and CopperInsufficient evidence
- Omeprazole and ZincInsufficient evidence
- Omeprazole and DoxycyclineInsufficient evidence
- Omeprazole and MetforminInsufficient evidence
- Omeprazole and LisinoprilInsufficient evidence
- Omeprazole and CoQ10 (Coenzyme Q10)Insufficient evidence
- Omeprazole and ProbioticsInsufficient evidence
- Omeprazole and CreatineInsufficient evidence
- Omeprazole and Vitamin KInsufficient evidence
- Omeprazole and LevothyroxineMonitor
- Omeprazole and Vitamin DInsufficient evidence
- Omeprazole and SpironolactoneInsufficient evidence
- Omeprazole and TurmericInsufficient evidence
- Omeprazole and PotassiumMonitor
Sources
Last reviewed 2026-08-22
Medical information disclaimer: this information is general and educational. It does not diagnose conditions, prescribe treatment, or determine whether a combination is safe for you personally. Follow your prescription label and ask a pharmacist or clinician before starting, stopping, or combining products. Full disclaimer.