Can I Take These?

Can You Take Metformin and Omeprazole Together?

No documented interaction was identified between metformin and omeprazole in the sources reviewed.

No documented interaction identifiedEvidence: Moderate

See the full Metformin page and Omeprazole page for other reviewed interactions and reference information.

What the interaction means

Metformin's FDA label does not mention omeprazole. Omeprazole's own FDA label does not mention metformin.

No documented interaction between Metformin and Omeprazole was identified in the authoritative sources reviewed. This is not a guarantee that no interaction exists for every dose, formulation, or individual -- it means the sources checked did not document one.

Practical context

Both Metformin's and Omeprazole's own current FDA labels were checked directly, full text, in both directions.

What the sources say

Omeprazole Delayed-Release Capsules — FDA Prescribing Information — American Health Packaging (via DailyMed, U.S. National Library of Medicine)Metformin Hydrochloride Tablets, USP — FDA Prescribing Information — Granules Pharmaceuticals Inc. (via DailyMed, U.S. National Library of Medicine)

Last reviewed 2026-08-23

Medical information disclaimer: this information is general and educational. It does not diagnose conditions, prescribe treatment, or determine whether a combination is safe for you personally. Follow your prescription label and ask a pharmacist or clinician before starting, stopping, or combining products. Full disclaimer.

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