Can You Take Ashwagandha and Omeprazole Together?

No documented interaction was identified between ashwagandha and omeprazole in the sources reviewed.

No documented interaction identifiedEvidence: Moderate

See the full Ashwagandha page and Omeprazole page for other reviewed interactions and reference information.

What the interaction means

NCCIH's ashwagandha fact sheet names six medication classes it may interact with (diabetes medicines, high blood pressure medicines, immunosuppressants, sedatives, anticonvulsants, and thyroid hormone medications) -- proton pump inhibitors are not among them, and omeprazole's own FDA label does not mention ashwagandha.

No documented interaction between Ashwagandha and Omeprazole was identified in the authoritative sources reviewed. This is not a guarantee that no interaction exists for every dose, formulation, or individual -- it means the sources checked did not document one.

Practical context

Ashwagandha's NCCIH fact sheet and omeprazole's FDA label were checked directly, full text, in both directions. NCCIH's list of six interacting medication classes for ashwagandha does not include proton pump inhibitors or other acid-reducing medicines.

What the sources say

Last reviewed 2026-08-25

Medical information disclaimer: this information is general and educational. It does not diagnose conditions, prescribe treatment, or determine whether a combination is safe for you personally. Follow your prescription label and ask a pharmacist or clinician before starting, stopping, or combining products. Full disclaimer.

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