Can I Take These?

Can You Take Ashwagandha and Metformin Together?

Ashwagandha is named by NCCIH as a supplement that may interact with diabetes medications, of which metformin is one.

MonitorEvidence: Moderate

See the full Ashwagandha page and Metformin page for other reviewed interactions and reference information.

What the interaction means

NCCIH's ashwagandha fact sheet states: "There is evidence that ashwagandha might interact with some medications, including those for diabetes and high blood pressure..." Metformin is a diabetes medication, per its own FDA label. NCCIH does not name metformin specifically or describe the mechanism or expected direction of effect beyond this class-level statement.

Why it may happen

Not further specified by NCCIH beyond classifying diabetes medications generally as a class ashwagandha might interact with; some research has explored ashwagandha's own effects on blood glucose.

Practical context

This is a class-level finding, not a metformin-specific one -- NCCIH does not give a spacing interval or dose-adjustment instruction. Anyone taking metformin who is considering ashwagandha should discuss it with their prescriber and watch for signs of low blood sugar if combined.

What the sources say

Metformin Hydrochloride Tablets, USP — FDA Prescribing Information — Granules Pharmaceuticals Inc. (via DailyMed, U.S. National Library of Medicine)Ashwagandha — National Center for Complementary and Integrative Health (NIH)

Last reviewed 2026-08-24

Medical information disclaimer: this information is general and educational. It does not diagnose conditions, prescribe treatment, or determine whether a combination is safe for you personally. Follow your prescription label and ask a pharmacist or clinician before starting, stopping, or combining products. Full disclaimer.

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