Can I Take These?

Can You Take Ciprofloxacin and Metformin Together?

No documented interaction was identified between ciprofloxacin and metformin in the sources reviewed.

No documented interaction identifiedEvidence: Moderate

See the full Ciprofloxacin page and Metformin page for other reviewed interactions and reference information.

What the interaction means

Ciprofloxacin's FDA label does not mention metformin anywhere. Metformin's FDA label does not mention ciprofloxacin or quinolones, including in its taxonomy list.

No documented interaction between Ciprofloxacin and Metformin was identified in the authoritative sources reviewed. This is not a guarantee that no interaction exists for every dose, formulation, or individual -- it means the sources checked did not document one.

Practical context

Both Ciprofloxacin's and Metformin's own current FDA labels were checked directly, full text, in both directions.

What the sources say

Ciprofloxacin Tablet — FDA Prescribing Information — Rising Pharmaceuticals, Inc. (via DailyMed, U.S. National Library of Medicine)Metformin Hydrochloride Tablets, USP — FDA Prescribing Information — Granules Pharmaceuticals Inc. (via DailyMed, U.S. National Library of Medicine)

Last reviewed 2026-08-23

Medical information disclaimer: this information is general and educational. It does not diagnose conditions, prescribe treatment, or determine whether a combination is safe for you personally. Follow your prescription label and ask a pharmacist or clinician before starting, stopping, or combining products. Full disclaimer.

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