Can I Take These?

Can You Take Ciprofloxacin and Doxycycline Together?

No documented interaction was identified between ciprofloxacin and doxycycline in the sources reviewed.

No documented interaction identifiedEvidence: Low

See the full Ciprofloxacin page and Doxycycline page for other reviewed interactions and reference information.

What the interaction means

Ciprofloxacin's FDA label's only mention of doxycycline is inside an unrelated bibliography citation (an animal pharmacokinetics study comparing several antibiotics), not a prose statement about combining the two drugs. Doxycycline's own FDA label does not mention ciprofloxacin at all.

No documented interaction between Ciprofloxacin and Doxycycline was identified in the authoritative sources reviewed. This is not a guarantee that no interaction exists for every dose, formulation, or individual -- it means the sources checked did not document one.

Practical context

Both drugs are commonly prescribed antibiotics from different classes (fluoroquinolone and tetracycline); neither drug's own current FDA label documents a direct interaction between them.

What the sources say

Doxycycline Hyclate — FDA Prescribing Information — Sun Pharmaceutical Industries, Inc. (via DailyMed, U.S. National Library of Medicine)Ciprofloxacin Tablet — FDA Prescribing Information — Rising Pharmaceuticals, Inc. (via DailyMed, U.S. National Library of Medicine)

Last reviewed 2026-08-23

Medical information disclaimer: this information is general and educational. It does not diagnose conditions, prescribe treatment, or determine whether a combination is safe for you personally. Follow your prescription label and ask a pharmacist or clinician before starting, stopping, or combining products. Full disclaimer.

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