Can I Take These?

Can You Take Ciprofloxacin and Doxycycline Together?

No documented interaction was identified between ciprofloxacin and doxycycline in the sources reviewed.

No documented interaction identifiedEvidence: Low

What the interaction means

Ciprofloxacin's FDA label's only mention of doxycycline is inside an unrelated bibliography citation (an animal pharmacokinetics study comparing several antibiotics), not a prose statement about combining the two drugs. Doxycycline's own FDA label does not mention ciprofloxacin at all.

No documented interaction was identified in the authoritative sources reviewed. This is not a guarantee that no interaction exists for every dose, formulation, or individual -- it means the sources checked did not document one.

Practical context

Both drugs are commonly prescribed antibiotics from different classes (fluoroquinolone and tetracycline); neither drug's own current FDA label documents a direct interaction between them.

What the sources say

Doxycycline Hyclate — FDA Prescribing Information — Sun Pharmaceutical Industries, Inc. (via DailyMed, U.S. National Library of Medicine)Ciprofloxacin Tablet — FDA Prescribing Information — Rising Pharmaceuticals, Inc. (via DailyMed, U.S. National Library of Medicine)

Last reviewed 2026-08-23

Medical information disclaimer: this information is general and educational. It does not diagnose conditions, prescribe treatment, or determine whether a combination is safe for you personally. Follow your prescription label and ask a pharmacist or clinician before starting, stopping, or combining products. Full disclaimer.

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