Can I Take These?

Can You Take Ciprofloxacin and Vitamin B12 Together?

No documented interaction was identified between ciprofloxacin and vitamin B12 in the sources reviewed.

No documented interaction identifiedEvidence: Moderate

What the interaction means

Ciprofloxacin's FDA label does not mention vitamin B12 as an interaction. The NIH ODS vitamin B12 fact sheet's own interactions section names gastric acid inhibitors and metformin specifically -- ciprofloxacin is not named.

No documented interaction was identified in the authoritative sources reviewed. This is not a guarantee that no interaction exists for every dose, formulation, or individual -- it means the sources checked did not document one.

Practical context

Both substances' own current authoritative sources were checked directly, full text, in both directions.

What the sources say

Vitamin B12 — Consumer — NIH Office of Dietary SupplementsCiprofloxacin Tablet — FDA Prescribing Information — Rising Pharmaceuticals, Inc. (via DailyMed, U.S. National Library of Medicine)

Last reviewed 2026-08-23

Medical information disclaimer: this information is general and educational. It does not diagnose conditions, prescribe treatment, or determine whether a combination is safe for you personally. Follow your prescription label and ask a pharmacist or clinician before starting, stopping, or combining products. Full disclaimer.

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