Can I Take These?

Can You Take CoQ10 (Coenzyme Q10) and Vitamin B12 Together?

No documented interaction was identified between CoQ10 and vitamin B12 in the sources reviewed.

No documented interaction identifiedEvidence: Moderate

See the full CoQ10 (Coenzyme Q10) page and Vitamin B12 page for other reviewed interactions and reference information.

What the interaction means

NCCIH's CoQ10 page names exactly three interaction concerns -- warfarin, insulin, and some cancer treatments -- and vitamin B12 is not among them. Vitamin B12's own fact sheet interactions section names only gastric acid inhibitors and metformin -- CoQ10 is not among them either.

No documented interaction between CoQ10 (Coenzyme Q10) and Vitamin B12 was identified in the authoritative sources reviewed. This is not a guarantee that no interaction exists for every dose, formulation, or individual -- it means the sources checked did not document one.

Practical context

NCCIH's CoQ10 page and vitamin B12's NIH ODS fact sheet were checked directly, full text, in both directions. Neither source names the other.

What the sources say

Vitamin B12 — Consumer — NIH Office of Dietary SupplementsCoenzyme Q10 — National Center for Complementary and Integrative Health (NIH)

Last reviewed 2026-08-25

Medical information disclaimer: this information is general and educational. It does not diagnose conditions, prescribe treatment, or determine whether a combination is safe for you personally. Follow your prescription label and ask a pharmacist or clinician before starting, stopping, or combining products. Full disclaimer.

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