CoQ10 (Coenzyme Q10)
A compound naturally present in the body, sold as a dietary supplement, with limited evidence supporting benefits for most conditions studied.
What it is
Coenzyme Q10 (CoQ10) is a substance naturally present in the human body, with the highest levels in the heart, liver, kidneys, and pancreas. It's available in the U.S. as a dietary supplement. Research on its effectiveness for heart disease, heart failure, and statin-related muscle pain has been inconclusive; a major NIH-funded study found it does not improve symptoms in early Parkinson's disease. NCCIH describes it as generally safe with only mild reported side effects.
Known interaction categories
- Insufficient evidence
- Monitor
- Use caution
Published interaction pages on this site
- CoQ10 (Coenzyme Q10) and MelatoninInsufficient evidence
- CoQ10 (Coenzyme Q10) and MagnesiumInsufficient evidence
- CoQ10 (Coenzyme Q10) and AtorvastatinMonitor
- CoQ10 (Coenzyme Q10) and WarfarinUse caution
- CoQ10 (Coenzyme Q10) and CiprofloxacinInsufficient evidence
- CoQ10 (Coenzyme Q10) and CalciumInsufficient evidence
- CoQ10 (Coenzyme Q10) and SpironolactoneInsufficient evidence
- CoQ10 (Coenzyme Q10) and IronInsufficient evidence
- CoQ10 (Coenzyme Q10) and Vitamin B12Insufficient evidence
- CoQ10 (Coenzyme Q10) and PotassiumInsufficient evidence
- CoQ10 (Coenzyme Q10) and St. John's WortInsufficient evidence
- CoQ10 (Coenzyme Q10) and Vitamin DInsufficient evidence
- CoQ10 (Coenzyme Q10) and CopperInsufficient evidence
- CoQ10 (Coenzyme Q10) and MetforminInsufficient evidence
- CoQ10 (Coenzyme Q10) and CaffeineInsufficient evidence
- CoQ10 (Coenzyme Q10) and CreatineInsufficient evidence
- CoQ10 (Coenzyme Q10) and SertralineInsufficient evidence
- CoQ10 (Coenzyme Q10) and DoxycyclineInsufficient evidence
- CoQ10 (Coenzyme Q10) and LisinoprilInsufficient evidence
- CoQ10 (Coenzyme Q10) and OmeprazoleInsufficient evidence
- CoQ10 (Coenzyme Q10) and ProbioticsInsufficient evidence
- CoQ10 (Coenzyme Q10) and LevothyroxineInsufficient evidence
- CoQ10 (Coenzyme Q10) and Vitamin KInsufficient evidence
- CoQ10 (Coenzyme Q10) and TurmericInsufficient evidence
- CoQ10 (Coenzyme Q10) and ZincInsufficient evidence
Sources
Last reviewed 2026-08-22
Medical information disclaimer: this information is general and educational. It does not diagnose conditions, prescribe treatment, or determine whether a combination is safe for you personally. Follow your prescription label and ask a pharmacist or clinician before starting, stopping, or combining products. Full disclaimer.