Can You Take CoQ10 (Coenzyme Q10) and Vitamin E Together?

No documented interaction was identified between vitamin E and CoQ10 in the sources reviewed.

No documented interaction identifiedEvidence: Moderate

See the full CoQ10 (Coenzyme Q10) page and Vitamin E page for other reviewed interactions and reference information.

What the interaction means

Vitamin E's own NIH ODS Health Professional fact sheet names two interaction concerns -- bleeding risk with anticoagulant/antiplatelet medications above 400 IU/day, and reduced chemotherapy/radiotherapy effectiveness -- and CoQ10 is not among them. NCCIH's CoQ10 page does not mention vitamin E or tocopherol.

No documented interaction between CoQ10 (Coenzyme Q10) and Vitamin E was identified in the authoritative sources reviewed. This is not a guarantee that no interaction exists for every dose, formulation, or individual -- it means the sources checked did not document one.

Practical context

Vitamin E's NIH ODS fact sheet and NCCIH's CoQ10 page were checked directly, full text, in both directions. Vitamin E's own named interaction concerns do not include CoQ10 or other supplements.

What the sources say

Last reviewed 2026-08-25

Medical information disclaimer: this information is general and educational. It does not diagnose conditions, prescribe treatment, or determine whether a combination is safe for you personally. Follow your prescription label and ask a pharmacist or clinician before starting, stopping, or combining products. Full disclaimer.

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