Can I Take These?

Can You Take Ibuprofen and Vitamin E Together?

No documented interaction was identified between vitamin E and ibuprofen in the sources reviewed, though both can affect platelet function.

No documented interaction identifiedEvidence: Moderate

See the full Ibuprofen page and Vitamin E page for other reviewed interactions and reference information.

What the interaction means

Vitamin E's own NIH ODS Health Professional fact sheet does not mention "NSAID," "nonsteroidal," or "ibuprofen" anywhere; its only documented bleeding-risk interaction language names "anticoagulant or antiplatelet medications," exemplified solely by warfarin (an anticoagulant). Ibuprofen's own FDA label does not mention vitamin E or tocopherol anywhere.

No documented interaction was identified in the authoritative sources reviewed. This is not a guarantee that no interaction exists for every dose, formulation, or individual -- it means the sources checked did not document one.

Why it may happen

Not established as a documented interaction by either source. Ibuprofen, an NSAID, has some platelet-function effects, and vitamin E can inhibit platelet aggregation at high doses, so a shared mechanism is plausible but is not named as a specific caution in either primary source.

Practical context

This pair was checked with particular care given the shared bleeding-risk mechanism flagged in this project's research brief. Unlike the vitamin E + aspirin pair (where aspirin is directly discussed in vitamin E's own fact sheet), NSAIDs/ibuprofen are not mentioned anywhere in that same fact sheet's text.

What the sources say

Ibuprofen Tablets, USP — FDA Prescribing Information — Ascend Laboratories, LLC (via DailyMed, U.S. National Library of Medicine)Vitamin E - Health Professional Fact Sheet — NIH Office of Dietary Supplements

Last reviewed 2026-08-24

Medical information disclaimer: this information is general and educational. It does not diagnose conditions, prescribe treatment, or determine whether a combination is safe for you personally. Follow your prescription label and ask a pharmacist or clinician before starting, stopping, or combining products. Full disclaimer.

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