Can You Take St. John's Wort and Vitamin E Together?
No documented interaction was identified between vitamin E and St. John's Wort in the sources reviewed.
See the full St. John's Wort page and Vitamin E page for other reviewed interactions and reference information.
What the interaction means
Vitamin E's own NIH ODS and MedlinePlus sources do not name St. John's Wort anywhere. NCCIH's St. John's Wort page discusses its interactions with various medications but does not mention vitamin E or tocopherol.
No documented interaction was identified in the authoritative sources reviewed. This is not a guarantee that no interaction exists for every dose, formulation, or individual -- it means the sources checked did not document one.
Practical context
Both substances' own current authoritative sources were checked directly, full text, in both directions.
What the sources say
Last reviewed 2026-08-24
Medical information disclaimer: this information is general and educational. It does not diagnose conditions, prescribe treatment, or determine whether a combination is safe for you personally. Follow your prescription label and ask a pharmacist or clinician before starting, stopping, or combining products. Full disclaimer.
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- St. John's Wort and AmlodipineInsufficient evidence
- St. John's Wort and IbuprofenInsufficient evidence
- St. John's Wort and EscitalopramUse caution
- Vitamin E and OmeprazoleInsufficient evidence
- Vitamin E and SertralineInsufficient evidence
- Vitamin E and Vitamin B12Insufficient evidence
- Vitamin E and SpironolactoneInsufficient evidence
- Vitamin E and TurmericInsufficient evidence
- Vitamin E and CalciumInsufficient evidence
- Vitamin E and CiprofloxacinInsufficient evidence
- Vitamin E and Vitamin KMonitor
- Vitamin E and AtorvastatinInsufficient evidence
- Vitamin E and CaffeineInsufficient evidence
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- Vitamin E and CoQ10 (Coenzyme Q10)Insufficient evidence
- Vitamin E and CreatineInsufficient evidence
- Vitamin E and DoxycyclineInsufficient evidence
- Vitamin E and IronInsufficient evidence
- Vitamin E and LevothyroxineInsufficient evidence
- Vitamin E and LisinoprilInsufficient evidence
- Vitamin E and MagnesiumInsufficient evidence
- Vitamin E and MetforminInsufficient evidence
- Vitamin E and MelatoninInsufficient evidence
- Vitamin E and ProbioticsInsufficient evidence
- Vitamin E and Vitamin CMonitor
- Vitamin E and Omega-3 / Fish OilInsufficient evidence
- Vitamin E and AshwagandhaInsufficient evidence
- Vitamin E and Folate / Folic AcidInsufficient evidence
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- Vitamin E and AspirinUse caution
- Vitamin E and IbuprofenInsufficient evidence
- Vitamin E and EscitalopramInsufficient evidence
- Vitamin E and PotassiumInsufficient evidence
- Vitamin E and WarfarinMonitor
- Vitamin E and Vitamin DInsufficient evidence
- Vitamin E and ZincInsufficient evidence