Can I Take These?

Can You Take Folate / Folic Acid and Vitamin E Together?

No documented interaction was identified between vitamin E and folate in the sources reviewed.

No documented interaction identifiedEvidence: Moderate

See the full Folate / Folic Acid page and Vitamin E page for other reviewed interactions and reference information.

What the interaction means

Vitamin E's own NIH ODS fact sheet does not mention folate or folic acid anywhere. Folate's own NIH ODS fact sheet names methotrexate, phenytoin, carbamazepine, valproate, and sulfasalazine as medication interactions, plus a masking effect on vitamin B12 deficiency, and does not mention vitamin E or tocopherol.

No documented interaction was identified in the authoritative sources reviewed. This is not a guarantee that no interaction exists for every dose, formulation, or individual -- it means the sources checked did not document one.

Practical context

Both substances' own current authoritative fact sheets were checked directly, full text, in both directions.

What the sources say

Vitamin E - Health Professional Fact Sheet — NIH Office of Dietary SupplementsFolate — Health Professional Fact Sheet — NIH Office of Dietary Supplements

Last reviewed 2026-08-24

Medical information disclaimer: this information is general and educational. It does not diagnose conditions, prescribe treatment, or determine whether a combination is safe for you personally. Follow your prescription label and ask a pharmacist or clinician before starting, stopping, or combining products. Full disclaimer.

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