Can You Take Vitamin E and Zinc Together?

No documented interaction was identified between vitamin E and zinc in the sources reviewed, though both appear together in the AREDS eye-health formula.

No documented interaction identifiedEvidence: Moderate

See the full Vitamin E page and Zinc page for other reviewed interactions and reference information.

What the interaction means

Vitamin E's own NIH ODS and MedlinePlus sources do not name zinc anywhere. The NIH ODS zinc fact sheet mentions vitamin E once, in its Age-related macular degeneration section, describing the AREDS supplement formula studied in clinical trials: "The ingredients in the supplements were: 80 mg zinc plus vitamin E, vitamin C, copper, and either beta-carotene or lutein and zeaxanthin." This is a co-formulation ingredient listing, not a stated interaction between zinc and vitamin E.

No documented interaction was identified in the authoritative sources reviewed. This is not a guarantee that no interaction exists for every dose, formulation, or individual -- it means the sources checked did not document one.

Practical context

Zinc and vitamin E are co-listed as ingredients in the AREDS/AREDS2 eye-health supplement formula studied for age-related macular degeneration, but the zinc fact sheet does not describe them as interacting with each other pharmacologically; this was deliberately not treated as a documented interaction, consistent with how this project treats co-listing without a stated interaction claim.

What the sources say

Last reviewed 2026-08-24

Medical information disclaimer: this information is general and educational. It does not diagnose conditions, prescribe treatment, or determine whether a combination is safe for you personally. Follow your prescription label and ask a pharmacist or clinician before starting, stopping, or combining products. Full disclaimer.

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