Can You Take Vitamin B12 and Zinc Together?
No documented interaction was identified between vitamin B12 and zinc in the sources reviewed.
What the interaction means
Zinc's NIH fact sheet's interactions section names quinolone/tetracycline antibiotics, penicillamine, and thiazide diuretics -- vitamin B12 is not among them. Vitamin B12's own fact sheet does not mention zinc.
No documented interaction was identified in the authoritative sources reviewed. This is not a guarantee that no interaction exists for every dose, formulation, or individual -- it means the sources checked did not document one.
Practical context
Both substances' own current authoritative sources were checked directly, full text, in both directions.
What the sources say
Last reviewed 2026-08-23
Medical information disclaimer: this information is general and educational. It does not diagnose conditions, prescribe treatment, or determine whether a combination is safe for you personally. Follow your prescription label and ask a pharmacist or clinician before starting, stopping, or combining products. Full disclaimer.
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- Zinc and MagnesiumMonitor
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- Zinc and CopperMonitor
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- Zinc and PotassiumInsufficient evidence
- Zinc and St. John's WortInsufficient evidence
- Zinc and MetforminInsufficient evidence
- Zinc and AtorvastatinInsufficient evidence
- Zinc and LevothyroxineInsufficient evidence
- Zinc and LisinoprilInsufficient evidence
- Zinc and SertralineInsufficient evidence
- Zinc and OmeprazoleInsufficient evidence
- Zinc and MelatoninInsufficient evidence
- Zinc and Vitamin DInsufficient evidence
- Zinc and Vitamin KInsufficient evidence
- Zinc and ProbioticsInsufficient evidence
- Zinc and CaffeineInsufficient evidence
- Zinc and CreatineInsufficient evidence
- Zinc and SpironolactoneInsufficient evidence
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- Zinc and CoQ10 (Coenzyme Q10)Insufficient evidence
- Zinc and TurmericInsufficient evidence