Can You Take Vitamin B12 and Zinc Together?

No documented interaction was identified between vitamin B12 and zinc in the sources reviewed.

No documented interaction identifiedEvidence: Moderate

See the full Vitamin B12 page and Zinc page for other reviewed interactions and reference information.

What the interaction means

Zinc's NIH fact sheet's interactions section names quinolone/tetracycline antibiotics, penicillamine, and thiazide diuretics -- vitamin B12 is not among them. Vitamin B12's own fact sheet does not mention zinc.

No documented interaction between Vitamin B12 and Zinc was identified in the authoritative sources reviewed. This is not a guarantee that no interaction exists for every dose, formulation, or individual -- it means the sources checked did not document one.

Practical context

Both Vitamin B12's and Zinc's own current authoritative sources were checked directly, full text, in both directions.

What the sources say

Last reviewed 2026-08-23

Medical information disclaimer: this information is general and educational. It does not diagnose conditions, prescribe treatment, or determine whether a combination is safe for you personally. Follow your prescription label and ask a pharmacist or clinician before starting, stopping, or combining products. Full disclaimer.

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