Can You Take Probiotics and Zinc Together?
No documented interaction was identified between probiotics and zinc in the sources reviewed.
What the interaction means
The NIH Office of Dietary Supplements' zinc fact sheet's interactions section names only quinolone antibiotics, tetracycline antibiotics, penicillamine, and thiazide diuretics -- probiotics are not named. NCCIH's probiotics page does not mention zinc.
No documented interaction was identified in the authoritative sources reviewed. This is not a guarantee that no interaction exists for every dose, formulation, or individual -- it means the sources checked did not document one.
Practical context
Both substances' own current authoritative sources were checked directly, full text, in both directions.
What the sources say
Last reviewed 2026-08-23
Medical information disclaimer: this information is general and educational. It does not diagnose conditions, prescribe treatment, or determine whether a combination is safe for you personally. Follow your prescription label and ask a pharmacist or clinician before starting, stopping, or combining products. Full disclaimer.
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- Zinc and MagnesiumMonitor
- Zinc and WarfarinInsufficient evidence
- Zinc and IronMonitor
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- Zinc and CopperMonitor
- Zinc and CalciumInsufficient evidence
- Zinc and Vitamin B12Insufficient evidence
- Zinc and PotassiumInsufficient evidence
- Zinc and St. John's WortInsufficient evidence
- Zinc and MetforminInsufficient evidence
- Zinc and AtorvastatinInsufficient evidence
- Zinc and LevothyroxineInsufficient evidence
- Zinc and LisinoprilInsufficient evidence
- Zinc and SertralineInsufficient evidence
- Zinc and OmeprazoleInsufficient evidence
- Zinc and MelatoninInsufficient evidence
- Zinc and Vitamin DInsufficient evidence
- Zinc and Vitamin KInsufficient evidence
- Zinc and CaffeineInsufficient evidence
- Zinc and CreatineInsufficient evidence
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- Zinc and DoxycyclineUse caution
- Zinc and CoQ10 (Coenzyme Q10)Insufficient evidence
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