Can I Take These?

Can You Take Magnesium and Probiotics Together?

No documented interaction was identified between magnesium and probiotics in the sources reviewed.

No documented interaction identifiedEvidence: Moderate

See the full Magnesium page and Probiotics page for other reviewed interactions and reference information.

What the interaction means

Magnesium's NIH ODS fact sheet names bisphosphonates, certain antibiotics, diuretics, and acid reflux/peptic ulcer drugs as its documented drug interactions -- probiotics are not among them. NCCIH's probiotics page's only medication-related discussion anywhere is research on reducing antibiotic-associated diarrhea, and does not mention magnesium.

No documented interaction between Magnesium and Probiotics was identified in the authoritative sources reviewed. This is not a guarantee that no interaction exists for every dose, formulation, or individual -- it means the sources checked did not document one.

Practical context

Magnesium's NIH ODS fact sheet and NCCIH's probiotics page were checked directly, full text, in both directions. Neither source names the other.

What the sources say

Magnesium — Consumer — NIH Office of Dietary SupplementsProbiotics: What You Need To Know — National Center for Complementary and Integrative Health (NIH)

Last reviewed 2026-08-25

Medical information disclaimer: this information is general and educational. It does not diagnose conditions, prescribe treatment, or determine whether a combination is safe for you personally. Follow your prescription label and ask a pharmacist or clinician before starting, stopping, or combining products. Full disclaimer.

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