Can I Take These?

Can You Take Folate / Folic Acid and Zinc Together?

No documented interaction was identified between folate and zinc in the sources reviewed.

No documented interaction identifiedEvidence: Moderate

See the full Folate / Folic Acid page and Zinc page for other reviewed interactions and reference information.

What the interaction means

Folate's NIH ODS fact sheets name five interacting medications -- methotrexate, phenytoin, carbamazepine, valproate, and sulfasalazine -- and zinc is not among them. The NIH Office of Dietary Supplements' zinc fact sheet does not mention folate or folic acid.

No documented interaction between Folate / Folic Acid and Zinc was identified in the authoritative sources reviewed. This is not a guarantee that no interaction exists for every dose, formulation, or individual -- it means the sources checked did not document one.

Practical context

Folate's NIH ODS fact sheets and zinc's NIH ODS fact sheet were checked directly, full text, in both directions. Folate's own named interacting medications do not include zinc or minerals generally.

What the sources say

Folate — Consumer — NIH Office of Dietary SupplementsZinc — Consumer — NIH Office of Dietary Supplements

Last reviewed 2026-08-25

Medical information disclaimer: this information is general and educational. It does not diagnose conditions, prescribe treatment, or determine whether a combination is safe for you personally. Follow your prescription label and ask a pharmacist or clinician before starting, stopping, or combining products. Full disclaimer.

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